The Association's activities are driven by sub-committees, which report to the Executive Committee. Each sub-committee has between four and five members, each of whom is a specialist in the field. Operational sub-committees are headed by chairpersons who sit on the Executive Committee representing their sub-committee. The following are the sub-committees:
| Name of Sub Committee | Purpose |
| Audit | To ensure there is transparency &accountability in all of the Association's financial activities and transactions, and to safeguard the Association's assets. |
| Capital Markets | To support the creation of a vibrant capital market environment for SMEs in Zimbabwe. |
| Decentralization | To encourage the formation and expansion of SMEs in areas outside of the major towns and cities, in line with the "growth point" strategy previously adopted by Government. |
| Environmental | To develop a culture of incorporating environmentally friendly business practices in SMEs. |
| Finance | Establish and maintain a robust, world-class financial management environment within the SME Association of Zimbabwe. |
| Fund-raising | Oversight of the Association's income based and developmental strategies aimed at generating revenues to support the activities and expansion of the Association. |
| Human Resources | To create and maintain a world-class Human Resources function within the SME Association, which adheres to best practice, and attracts and retains the best talent within the Association. |
| Infrastructure | Create world-class infrastructure for members of the Association and for the Zimbabwean economy in general. |
| Lobbying & Advocacy | To create a vibrant, non-confrontational and effective lobbying and advocacy function for the Association which continuously seeks a level and fair playing field for SMEs in Zimbabwe and on the global market. |
| Media & Communications | Create a unified, powerful and progressive voice, brand and presence for the Association in Zimbabwe and abroad. |
| Research & Development | Ensure that the Association and its members attain and maintain a position of leadership in the area of SME development through the application of research and development techniques. |
| Training & Development | To create a world-class training program for SMEs that will give them adequate training to expand from being small enterprises to being large corporations with global impact. |